Important, changing other user privileges on a system may produce the same result as below and be nothing to do with S&D!
However, if Internet Exlorer starts delivering this error message...
"The operation has been canceled due to restrictions in place on this computer......." (windows 2000 professional screenshot)

AND you have either just installed S&D or have modified its settings
......You may need to change some of the settings in Spybot Search & Destroy AGAIN!

This will cause this, uncheck the third option, this will still stop sites
resetting your start page but will allow you to
change OPTIONS stuff otherwise. Locking the hosts file will prevent most hosts
hijackers (even unknown) from doing harm.
At least you now know where you set it....
Find these options in "Immunize"
click here or on image for larger screenshot